Windows 10 my cursor disappeared

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I will do this now and if this issue magically disappears will update this. NOTE: (KB4100403) is now being downloaded and installed, with a restart required. Hotfixes from Microsoft Update (agent version 4.48) install automatically. I believe Windows 10HP 64-bit is up to date,. Note that I have moved the Unifying Connector amongst the USB ports on the NUC. This issue does not occur on my Samsung laptop when using the same keyboard, mouse and connector. I am using a Logitech K350 wireless keyboard & M510 mouse with the Unifying connector and current software Logitech - SetPoint version 6.67.83 (64-bit). I will add that Logitech technical support did mention that they had received this issue from others and they thought that it may be a Windows or Office issue, but I can find nothing on Microsoft's board about this issue with a cursory (NPI) search. Is anyone else with a similarly configured NUC experiencing this issue? All advice welcome.

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I believe I can now isolate this issue to the NUC, and not Windows, Logitech or MS Office software.

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MS Office (Word, Outlook & Excel), this website, browsing bars on multiple Internet browsers), requiring that I left-click the mouse to restore the cursor. Several months ago, my cursor (not the pointer) began disappearing whenever I was typing in multiple applications, i.e.

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